PATTERNS AND PREVALENCE OF MICROBIAL AGENTS IN KIDNEY STONE PATIENTS IN A TERTIARY HOSPITAL
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Abstract
Methodology: This is a retrospective cross-sectional study of 110 patients referred from the urology and family medicine department of LASUTH conducted between October 2021 to September 2023. Inclusion criteria include all adult patients with abdominal-pelvic ultrasound or CT abdomen evidence of kidney stones who also had positive urine culture results weeks after kidney stone diagnosis. Demographic data, documentation of previous history of kidney stones and UTIs were also inferred. Data collected were analyzed using SPSS 23.0. Risk of UTI is predicted by logistic regression. Power of significance was set at 0.05.
Result: One hundred and ten stone formers were screened for data analysis. The mean age was 45.6±12.8 with a range of 19 – 78 years, there were more male 58(52.7%) than female 52(47.3%). The commonest stones were calcium oxalate 70.0%, calcium phosphate 15.5% and uric acid 10% respectively. The patterns of microbial infection were Proteus 44.4%, Haemolyticus 18.5%, E Coli 14.8%, Klebsiella 14.8% and Corynebacteria 7.5%. Proteus was significantly associated with uric acid and calcium oxalate stones with P value at 0,01 and 0.03 respectively while uric acid had 37 odds of developing UTI.
Conclusion: This study submitted that calcium oxalate and uric acid stone formers have very high predilection for the event of urinary tract infections. Early detection of the UTI and treatments have direct implication in preventing recurrent UTI which could progress to chronic pyelonephritis.
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