REFERENCE BASELINE VALUES FOR CALCANEAL QUANTITATIVE ULTRASOUND PARAMETERS IN NIGERIAN CHILDREN: RELATIONSHIP WITH BODY MASS INDEX AND SERUM CALCIUM
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Abstract
Objective: This study aimed to establish reference baseline values for calcaneal Quantitative Ultrasound Index (QUI) and Estimated Bone Mineral Density (eBMD) in healthy Nigerian children. It also investigated the relationship between BMI, serum calcium levels, and bone density.
Methods: The Sahara bone sonometer was used to measure the QUS parameters of 494 boys and 522 girls in this cross-sectional study. The participants' BMI and serum calcium levels were also measured. Pearson correlation coefficients and a multiple regression model were employed for the test of association and relationship.
Results: Baseline measurements of QUI and eBMD were available in boys with a mean (SD) age of 11.38 (2.32) years, and girls, with a mean (SD) age of 11.47 (2.92) years. The participants' mean QUI and eBMD (SD) were 94.91 (13.37) and 0.52 (0.08) g/cm², respectively, for boys and 92.46 (13.47) and 0.51 (0.09) g/cm² for girls. In both genders, age was a predictor of both QUI and eBMD (p < 0.05) while BMI was a predictor of both QUI and eBMD in only the girls (p < 0.05). Serum calcium had no relationship with the two QUS parameters (p > 0.05).
Conclusion: The study is the first to fill a critical gap in pediatric bone health data by establishing baseline QUI and eBMD values in Nigerian children.
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